yfmR [2019-01-03 14:37:08]

similar to ABC transporter (ATP-binding protein)

locus: BSU07370

pI: 5.00

mw: 70.94 kDa

protein length: 629 aa

gene length: 1887 bp

function: unknown

product: ABC transporter (ATP-binding protein)

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.4|Unknown ABC transporters]

Gene

Coordinates: 809,557 → 811,446

The protein

Catalyzed reaction/ biological activity

• a paraloguous protein from ''E. coli'' (EttA) gates [SW|ribosome] entry into the translation elongation cycle [Pubmed|24389465,24389466]

Paralogous protein(s)

• [protein|1F56D3275386BB54A774BFA045C09E36D1268471|YdiF], [protein|2F79DB15D359A127C2D833CC0465E18E1725F539|YkpA], [protein|47B644F334A0BD501E77A198A61CE0F22BAB3E5E|YfmM]

Structure

• [PDB|3J5S] (EttA from E. coli, 36% identity) [pubmed|24389465]
• [PDB|4FIN] (EttA from E. coli, 36% identity) [pubmed|24389466]

Expression and Regulation

Operons

• genes: [gene|F69F15198ACF8A8347C450EEC09F000EECEDEC41|yfmR]
  description: [pubmed|22383849]

Biological materials

Mutant

• MGNA-C234 (yfmR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2232 NBRP B. subtilis, Japan]
• BKE07370 (Δ[gene|F69F15198ACF8A8347C450EEC09F000EECEDEC41|yfmR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE07370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTTCCTATCAATCCTC, downstream forward: _UP4_TAAAAAGCGTGGCCGCAGCA
• BKK07370 (Δ[gene|F69F15198ACF8A8347C450EEC09F000EECEDEC41|yfmR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK07370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTTCCTATCAATCCTC, downstream forward: _UP4_TAAAAAGCGTGGCCGCAGCA

References

Reviews

• 24500425

Original publications

• 10092453,24389466,24389465,27006457